Cast[]
- Timmy The Tooth as Horton
- Sidney Cyclops as The Mayor of Who-ville
- Misty (from Pokémon) as Mrs Quillingan
- Sunny The Sun as Morton
- Bubbles Gum as Katie
- Annette as Sally
- Zira (from The Lion King 2) as Kangaa (they're both names of a last letter is "a")
- Emmett The Octopus as Kangaa's son
- Genie (from Aladdin) as The King Monkey
- Monkeys as Himself
- Speck of dust as Himself
- People of Who-ville as Himself
- Darkrai (from Pokémon) as Vlad
- Susie Carmichael (from Rugrats)/Shenzi (from The Lion King) as Hedy Hooly
- Ms. Sweety as Helen
- Happy (from Snow White) as Jojo