Cast[]
- Duke as Gary
- Chloe as Kira
- Hank (from Journey 2: The Mysterious Island) as Scorch
- Kailani (from Journey 2: The Mysterious Island) as Lena
- Max as Kip
- Mel as Shanker
- Gru (from Despicable Me) as Doc
- Anges (from Despicable Me) as Gabby Babblebrook
- Grammy Norma (from Dr. Seuss' The Lorax) as Io
- Silas Ramsbottom (from Despicable Me 2) as Thurman
- Sean (from Journey 2: The Mysterious Island) as Ralph
- E.B. (from HOP) as Hazmat 1 Peter
- Dr. Nefario (from Despicable Me) as Hazmat 2 Quentin
- Snowball as Hazmat 3 Bruce
- Max and Duke's Owner as Hazmat 4 Christopher
- The Once-ler's Mom (from Dr. Seuss' The Lorax) as Hazmat 5 Marty
- Vector (from Despicable Me) as Hazmat 6 George