Cast[]
- Clifford the Big Red Dog as Mario (Both red and main stars)
- Mr. Conductor as Luigi
- T-Bone as Yoshi (Both best friends and sidekicks to Clifford and Mario)
- Emily Elizabeth as Peach
- Sagwa as Daisy
- Baby Bop as Birdo
- Buzz as Wario
- Delete as Waluigi
- Norville as Mallow
- Coop as Toadswoth
- D.W. as Pauline
- Stacy Jones as Rosalina
- Papa Bear as Donkey Kong
- Mama Bear as Candy Kong
- Curious George as Donkey Kong Jr.
- Elmo as Diddy Kong
- Princess Presto as Dixie Kong
- Wonder Red as Tiny Kong
- Schemee as Swanky Kong
- The Brain as Lanky Kong
- Binky as Chunky Kong
- Noah as Wrinkly Kong
- Buster as King K. Rool
- Birthday Girl as Wendy Koopa
- Brother Bear as Toad
- Sister Bear as Toadette
- Glen as Bowser Jr.
- Hacker as Bowser
- BJ as Oogtar
- Timmy as Lemmy "Hip" Koopa
- Tommy as Iggy "Hop" Koopa
- Energy Monster as Peter Piranha
- The Butcher as tatanga