Cast[]
- Jimmy Neutron as Yakko Warner
- Carl Wheezer as Wakko Warner
- Cindy Vortex as Dot Warner
- Mr. Neutron as Dr. Otto Scratchansniff
- Mrs. Neutron as Hello Nurse
- Comander Baker as Thaddeus Plotz
- Giggles the Clown as Ralph the Guard
- Principal Wiloughby as Mr. Director
- Ms. Fowl as Miss Flamiel
- Ooblar as Pinky
- Eustace Strych as Brain
- Beautiful Gorgeous as Slappy Squirrel
- Nick Dean as Skippy Squirrel
- Zix as Pesto
- Travoltron as Bobby
- Tee as Squit
- Elke Elkberg as Mindy
- Goddard as Buttons
- Libby Folfax as Rita
- Sheen Estevez as Runt
- Ebenzer Wheezer as Flavio Hippo
- Martha Wheezer as Marita Hippo
- Betty Quinlan as Minerva Mink
- Jet Fusion as Walter Wolf
- Professor Calamitous as King Salazar