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1. VP-16
 
1. VP-16
*[[Schaut]] , Nikki
+
*[[Image:Tinysunfl.jpg]][[Schaut]], Nikki
   
 
2. Vioxx
 
2. Vioxx
Line 8: Line 8:
   
 
3. Gleevec
 
3. Gleevec
*[[Schaut]] , Nikki - tumor started growing, stopped drug
+
*[[Image:Tinysunfl.jpg]][[Schaut]], Nikki - tumor started growing, stopped drug
   
 
4. Celebrex
 
4. Celebrex
*[[Payne]] , Steve
+
*[[Image:Tinysunfl.jpg]][[Payne]], Steven
 
*[[Image:Tinysunfl.jpg]][[Robertson]],Nathan
   
 
5. Irinotecan and Temodar
 
5. Irinotecan and Temodar
*[[Ricardo]]
 
   
  +
*[[Image:Tinysunfl.jpg]][[Ricardo]]
*[[Robertson]], Nathan
 
  +
*[[Image:Tinysunfl.jpg]][[Robertson]],Nathan - stopped at 8 months, relapsed within 2 months
  +
  +
6. Sutent
  +
  +
*[[Image:Tinysunfl.jpg]][[Ricardo]]
  +
*[[Image:Tinysunfl.jpg]][[Robertson]],Nathan
  +
*[[Image:Tinysunfl.jpg]][[Skurat]], Steven
   
 
==Alternative and Complementary==
 
==Alternative and Complementary==
   
  +
[[Image:Tinysunfl.jpg]][[Braswell]], Christian
1.
 
*[[Braswell]], Chris
 
   
 
[[Image:Tinysunfl.jpg]][[Orantes]], Meliza
2.
 
*[[Orantes]], Meliza
 
   
 
==Clinical Studies==
 
==Clinical Studies==

Latest revision as of 20:02, 10 September 2010

Maintenance Drugs

1. VP-16

2. Vioxx

3. Gleevec

  • TinysunflSchaut, Nikki - tumor started growing, stopped drug

4. Celebrex

5. Irinotecan and Temodar

6. Sutent

Alternative and Complementary

TinysunflBraswell, Christian

TinysunflOrantes, Meliza

Clinical Studies

http://www3.interscience.wiley.com/cgi-bin/abstract/112151892/ABSTRACT?CRETRY=1&SRETRY=0

Response to vinorelbine and low-dose cyclophosphamide chemotherapy in two patients with desmoplastic small round cell tumor Andrea Ferrari, MD 1 *, Federica Grosso, MD 2, Silvia Stacchiotti, MD 2, Cristina Meazza, MD 1, Elena Zaffignani, MD 1, Alfonso Marchianò, MD 3, Michela Casanova, MD 1 1Pediatric Oncology Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano, Italy 2Adult Sarcoma Medical Oncology Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano, Italy 3Radiology Department, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano, Italy

email: Andrea Ferrari (andrea.ferrari@istitutotumori.mi.it)

  • Correspondence to Andrea Ferrari, Pediatric Oncology Unit, Istituto Nazionale Tumori, Via G. Venezian, 1-20133 Milano MI, Italy.

Keywords desmoplastic small round cell tumor • low-dose cyclophosphamide • metronomic therapy • vinorelbine


Abstract We report two cases of abdominal desmoplastic small round cell tumor (DSRCT) that showed a clinical response to the vinorelbine/low-dose cyclophosphamide combination that has been claimed to be effective for rhabdomyosarcoma. This observation may prompt further investigation into the activity of such a regimen in DSRCT patients with recurrent or refractory disease, with a view to a possible future role as maintenance therapy in controlling minimal residual disease in patients who achieve complete remission with intensive induction multimodality therapy. Pediatr Blood Cancer © 2005 Wiley-Liss, Inc.

DSRCT References

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