- Jane Kangaroo as Cruella DeVil
- Horton the Elephant as Kevin Shepard
- The White-Tufted Floozle Bird as Cole Shepard
- Joey as Waddlesworth
- Sarah Hall-Small as Oddball
- North-Going Zax and South-Going Zax as Le Pelt and Alonzo
- Cindy Lou Who as Agnes
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