Cast[]
- Arthur Read as Yakko Warner
- Buster Baxter as Wakko Warner
- Francine Frensky as Dot Warner
- David Read as Dr. Otto ScratchNSniff
- Jane Read as Hello Nurse
- Mr. Ratburn as Thaddeus Plotz
- Ed Crosswire Ralph T. Guard
- Mr. Haney Mr. Director
- Pickles as The Clown
- Francine's Grandfather as Baloney the Dinosaur
- D.W. Read as Elmyra Duff
- Bionic Bunny as Freakazoid
- Kindergarten Teacher as Prunella Flundergust
- Binky Barnes as Pinky
- Rattles as The Brain
- Nadine Flumberghast as Billie
- Sally MacGill as Slappy Squirrel
- George Lungdren as Skippy Squirrel
- 4th Grade Male Dog as Pesto
- Timmy Tibble as Bobby
- Tommy Tibble as Squit
- Pal as Buttons
- Kate Read as Mindy
- Muffy Crosswire as Rita
- Alan "The Brain" Powers as Runt
- Mime as The Mime
- Grandpa Dave as Flavio Hippo
- Grandma Thora as Marita Hippo
- Prunella Deegan as Katie Ka-Boom
- Molly MacDonald as Minerva Mink