Cast[]
- Winston as Thomas
- Sir Handel as Edward
- Peter Sam as Henry
- Merrick as Gordon
- Victor as James
- Stafford as Percy
- Stepney as Toby
- Butch as Duck
- Paxton and Norman as Donald and Douglas
- Thumper as Oliver
- Class 40 as Diesel
- Skarloey and Rheneas as Bill and Ben
- Duke as BoCo
- Henrietta as Daisy
- Caitlin as Mavis
- Toby as Stepney
- Annie as Emily
- Salty as Bertie
- Bertie as Salty
- Rusty as Harvey
- Max and Monty as Harry and Bert
- Charlie as Fergus
- Bill as Skarloey
- Ben as Rheneas
- Edward as Sir Handel
- Henry as Peter Sam
- Harvey as Rusty
- Dodge as Duncan
- BoCo as Duke
- Ferdinand as Freddie
- Den and Dart as Mighty Mac
- Kevin as Arthur
- Clarabel as Lady
- Spencer as Diesel 10
- Smudger and Duncan as Splatter and Dodge
- Stan Marsh (from South Park) as Sir Topham Hatt
- Wendy Testaburger (from South Park) as Lady Hatt
- Kyle Broflovski (from South Park) as Stephen Hatt
- Bebe Stevens (from South Park) as Bridget Hatt
- Eric Cartman (from South Park) as Jeremiah Jobling
- Skipper and Molly Mouse (from Skipper & Skeeto) as The Duke and Duchess of Boxford
- Hiro as Terence
- Scruff as Trevor
- Colin as Toad
- Byron as Derek
- Bulstrode as Bulgy
- Millie as Elizabeth
- Scruffey as George
- Connor as Murdoch
- Diesel 10 as Spencer
- Flora as Caroline
- Hector as Cranky
- George as Scruffey
- Splatter as Smudger
- Homer (from The Simpsons) as Mr. Percival
- Marge (from The Simpsons) as Mrs. Percival
- Jeremy as Harold
- Madge as Rosie
- Harold as Jeremy
- Old Slowcoach as Molly
- Nelson as Stephen
- Murdoch as Connor
- Mavis as Caitlin
- Elizabeth as Millie
- Rosie as Madge
- Thomas as Winston
- Cranky as Hector
- Percy as Stafford
- Duck as Butch
- Mighty Mac as Den and Dart
- Donald as Norman
- Douglas as Paxton
- Ned as Sidney
- Porter as Flynn
- Isabella as Belle
- Norman, Paxton and Sidney as The Horrid Lorries
- Bash as Jack
- Dash as Alfie
- Stephen as Nelson
- Belle as Isabella
- Derek as Byron
- Sidney as Ned
- Puffle (from Casey Jr and Friends) as Kelly
- Harry and Bert as Max and Monty
- Whiff as Buster
- Pete (from The Little Engine That Could) as Patrick
- Casey Jr (from Casey Jr and Friends) as Oliver (pack)
- Peter (from Family Guy) as The Foreman
- Lois (from Family Guy) as Miss Jenny
- Oliver as Thumper
- Toad as Colin
- Emily and Lady as Annie and Clarabel
- Daisy as Henrietta
- Gordon as Merrick
- Terence as Hiro
- James as Victor
- Arthur as Kevin
- Farnsworth (from The Little Engine That Could), Santa Fe and Dash 9 (Made up characters) as The Horrid Lorries
- Diesel as Class 40
- Caroline as Flora
- Bulgy as Bulstrode
- Buster as Whiff
- Trevor as Scruff