Groups by Treatment

Chemotherapy
First Line Protocols

A. Original P6 = 7 cycles of high dose chemo:
 * Cyclophosphamide Doxorubicin, Vincristine
 * Ifosfamide and Etoposide


 * Bidleman, Shawn
 * Jenkins, Craig
 * Marquis, Jordan
 * Schaut, Nikki
 * Spithakis, Anthony
 * Orantes, Meliza

B. P6 Variation (Kushner) = 6 cycles of high dose chemo substituting Topotecan and Cytoxan for Etoposide and Ifosomide
 * Luder, Kristen
 * Orgel, Greg

C. Ewings Protocol (based on same 5 drugs as Original P6 but with a different time frame of 9 or more cycles and lower dosage of Cyclophosphamide and the ifosfamide )
 * Spencer, Richard - Eicess EVAIA
 * Robertson, Nathan

D. Other Combinations

1. Adriamycin (Doxorubicin), Ifosfamide (Ifex), Vincristine
 * Cloer, Rebecca

2. Carboplatinum and Gemzar
 * Hodges, Marlena

3. Vincristine, Doxorubicin, Cyclophosphamide
 * Murray, Sheila

4. VIDE - 6 rounds =Vincristine, Ifosfamide, Doxorubicin, Etoposide
 * Middelman, Erik

5. Vincristine, Dactiamycin, Ifosfamide, Actinomycin, Carboplatin, Epirubicin, Etoposid
 * Kiyici, Michael

Other First Line Drugs

Vinblastin

Second Line Chemotherapy

Actinomycin

Alimta

Casodex (Bicalutamide)

Celebrex (Celecoxib)

Decitabine

Doxil

Gleevec

Irinotecan

Lupron

Thalidomide

VIP-E

Combinations


 * CCT High-dose chemotherapy
 * Cyclophosphamid 1500 mg/m2
 * Carboplatin 200 mg/m2
 * Thiotepa 125 mg/m2

Irinotecan and Temodar

Cytoxan and Topotecan

Docetaxel (Taxotere) and Gemcitabine (Gemzar)

Cisplatnum and Etoposide

Surgery

 * Debulking


 * Intraperitoneal hyperthermic chemoperfusion

Radiation

 * Precision Radiation

Stem Cell Transplant

 * Terms
 * Autologous transplants where patients receive their own stem cells.


 * Allogeneic transplants where patients receive stem cells from their brother, sister, or parent, or unknown matched donor.


 * Myeloablative Allogeneic Transplant -Patient receives high dose chemotherapy to prepare a disease free environment for 'new' host donated stem cells. Risk of patient developing a host vs graft reaction.


 * Nonmyeloablative Transplant -Low dose or standard chemotherapy used to prepare patient for stem cells. Takes a longer period of time to graft and also longer to notice a host vs graft reaction.


 * Mini Transplant is a reduced stem cell treatment with lower doses.


 * Tandem Transplant is two transplants in a row'


 * Graft vs Host -a reaction that can develop when a patients body rejects the donated 'new' stem cells.

See: Treatment Options Stem Cell


 * The following is a list of DSRCT patients who have received a Stem Cell rescue:


 * Falkenstein, Thomas
 * Hodges, Marlena
 * Luder, Kristen
 * Marquis, Jordan
 * Nailor, Kyle
 * Orgel, Greg
 * Ott, Keegan
 * Rodabaugh, Callie
 * Skurat, Steven
 * Spencer, Richard
 * Spithakis, Anthony
 * Vodicka, Ryan

Clinical Trials
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