Nicktoons/Madagascar

Animal Cast (toons only)

 * Danny Phantom as Alex
 * Timmy Turner as Marty
 * Dudley Puppy as Melman
 * Kitty Katswell as Gloria
 * Tommy Pickles as Skipper (they're the leaders of the pack)
 * Darwin Thornberry as Kowalski (they are both smart)
 * Donnie Thornberry as Rico (they are both crazy)
 * Chuckie Finster as Private (they're easily frightened)
 * Squidward Tentacles as King Julien XII (they're both selfish)
 * SpongeBob SquarePants as Maurice (SpongeBob/Maurice hangs out with Squidward/Julien a lot)
 * Patrick Star as Mort
 * Jimmy Neutron and Goddard as Mason and Phil
 * Jack and Maddie Fenton as Zuba and Florrie
 * Jack Rabbit as Moto Moto (Jack/Moto Moto flirted with Kitty/Gloria)
 * Vlad Plasmius as Makunga
 * Kimi Finster as Marlene

Human Cast (live action characters only)
More ideas?
 * Sam Puckett as Nana
 * Jade West as Captain Chantel DuBois