My Little Pony/Family Guy

Version 1

 * Twilight Sparkle as Peter
 * Princess Celestia as Lois
 * Pipsqueak as Chris
 * Scootaloo as Meg
 * Spike as Brian
 * Apple Bloom as Stewie
 * Snails as Bertram
 * Berry Punch as Quagmire
 * Pinkie Pie as Cleveland
 * Rainbow Dash as Joe
 * Applejack as Bonnie
 * Scootaloo as Susie
 * Princess Luna as Herbert
 * The Mayor of Ponyville as Adam West
 * Discord as Ernie the Giant Chicken
 * Big Macintosh as Shamus
 * Diamond Tiara as Olivia Feller

  Version 2

 * Pinkie Pie as Peter
 * Twilight Sparkle as Lois
 * Rainbow Dash as Chris
 * Twist as Meg
 * Apple Bloom as Stewie
 * Spike as Brian
 * Babs Seeds as Bertram
 * Princess Luna as Quagmire
 * Applejack as Cleveland
 * Fluttershy as Donna
 * Spitfire as Roberta
 * Tank as Tim
 * Scootaloo as Rollo
 * Big Macintosh as Joe
 * Cheerilee as Bonnie
 * Pumpkin Cake as Susie
 * Rarity as Jillian
 * Granny Smith as Herbert
 * Mayor Mare as Adam West
 * Gilda as Ernie the Giant Chicken
 * Snails as Tom Tucker
 * The Great and Powerful Trixie as Dianne Simmons
 * Zecora as Seamus
 * Flim and Flam as Vern and Jonny
 * Discord as James Woods
 * Owlysicous as the Evil Monkey
 * Queen Chrysalis as Death
 * Diamond Tiara as Oliviea Fulller
 * Silver Spoon as Victor
 * King Sombra as Evil Stewie

Version 3

 * Dr. Whooves as Peter
 * Twilight Sparkle as Lois (Twilight and Lois are both girlfriends to Dr. Whooves and Peter)
 * Applejack as Meg
 * Pipsqueak as Chris
 * Discord as Stewie
 * Spike as Brian
 * Braeburn as Quagmire
 * Marty (from Madagascar) as Cleveland
 * Big Macintosh as Joe
 * Mr. Carrot Cake as Mort Goldman
 * Fluttershy as Bonnie
 * Zacora as Loretta Brown
 * Apple Bloom as Susie
 * Pinkie Pie as Jillian
 * Mrs. Cup Cake as Muriel Goldman
 * Prince Blueblood as Carter
 * Rarity as Babs
 * Shining Armor as Patrick Pewterschmidt (Shining Armor and Patrick are both brothers with Twilight and Lois)
 * Trixie as Joyce Kinney
 * Rainbow Dash as Angela
 * Gilda as Connie D'Amico
 * Iron Will as Ernie the Giant Chicken
 * King Sombra as Death
 * Jet Set as Tom Tucker
 * Upper Crust as Dianne Simmons
 * Zeb (from G1) as Ollie Williams
 * Garble as Bertram
 * Cranky Doodle Donkey as Francis Griffin
 * Granny Smith as Thelma Griffin
 * Queen Chrysalis as Death's Mother