Groups by Chemotherapy

First Line Protocols
A. Original P6 = 7 cycles of high dose chemo:
 * Cycle: Adriamycin (Doxorubicin); Cytoxan (Cyclophosphamide); Vincristine with Mesna
 * Cycle: Etoposide (VP-16); Ifosfamide
 * Bender, Michael
 * Bidleman, Shawn
 * [[Image:Tinysunfl.jpg]]Daunoras, Jay
 * DeWalle, Mark
 * [[Image:Tinysunfl.jpg]]Hendricks, Haley
 * Hobbs, Caleb
 * Jenkins, Craig
 * [[Image:Tinysunfl.jpg]]Lunchuck, Timothy
 * [[Image:Tinysunfl.jpg]]Mays, Timothy
 * Schaut, Nikki
 * Spithakis, Anthony


 * 1. Modified by Dr Kushner
 * [[Image:Tinysunfl.jpg]]Adomanis, Jeff


 * 2. Altered P6
 * VACIME - Vincristine; Adriamycin (Doxorubicin); Cytoxan (Cyclophosphamide); Ifosfamide; Mesna; and Etoposide (VP-16), at very high doses.
 * [[Image:Tinysunfl.jpg]]Berman, Richard


 * 3. Modified P6
 * [[Image:Tinysunfl.jpg]]Bishnow, Brian


 * 4. P6 Variation - 6 cycles
 * Cycle: Ifosfamide, Etoposide - 2 cycles
 * Cycle: Vincristine, Doxorubicin, Cyclophosphamide - 4 cycles
 * [[Image:Tinysunfl.jpg]]Oberholzer, Chris

B. Kushner's DSRCT P6 Variation (Pediatric) = 6 cycles of high dose chemo
 * Cycle 1,2,3,6 = Adriamycin (Doxorubicin);Cytoxan (Cyclophosphamide); Vincristine
 * Cycle 4, 5= Cytoxan(Cyclophosphamide) and Topotecan
 * [[Image:Tinysunfl.jpg]]Brill, Steven
 * Luder, Kristen
 * Marquis, Jordan
 * Orgel, Greg
 * [[Image:Tinysunfl.jpg]]Pusey, Jade
 * [[Image:Tinysunfl.jpg]]Reichle, Brian


 * 1. Variation of Kushner's P6 = 7 cycles
 * Cycle 1, 5, 6, 7: Adriamycin (Doxorubicin);Cytoxan (Cyclophosphamide); Vincristine
 * Cycle 2: Etoposide (VP-16) and Ifosfamide (Ifex)
 * Cycle 3, 4: Cytoxan (Cyclophosphamide) and Topotecan
 * [[Image:Tinysunfl.jpg]]Wilson, Derek


 * 2. Variation of Kushner's P6
 * Cyle 1,2,3 : Adriamycin (Doxorubicin); Ifosfamide, and Vincristine
 * Cycle 4,5,6,9: Etoposide(VP-16); Ifosfamide
 * Cycle 7,8 : Cytoxan(Cyclophosphamide) and Topotecan
 * [[Image:Tinysunfl.jpg]]Budimir-Hussey, Jordan


 * 3. Variation of Kushner's P6
 * Cycle 1, 2, 3, 4, 5: Adriamycin (Doxorubicin);  Cytoxan (Cyclophosphamide) and Vincristine
 * Cycle 6, 7, 8, 9: Etoposide(VP-16); Ifosfamide
 * Cycle 10, 11 Topotecan everyday for 2 weeks
 * [[Image:Tinysunfl.jpg]]Carfi, Christopher

C. P6 'Adult' Variation = based on Original P6 but with a longer time frame (10-14 cycles) and lower doses and sometimes without the Etoposide (VP-16) and Ifosomide.
 * Orantes, Meliza

D. Ewings Protocol (based on same 5 drugs as Original P6 but with a different time frame of 8 or more cycles and lower dosage of Cytoxan(Cyclophosphamide) and Ifosomide).
 * Spencer, Richard - Eicess EVAIA
 * Robertson, Nathan

E. Other Chemo Combinations

1. Adriamycin(Doxorubicin); Ifosfamide(Ifex); and Vincristine
 * Cloer, Rebecca

2. Carboplatinum and Gemzar
 * Hodges, Marlena

3. Adriamycin(Doxorubicin); Cytoxan(Cyclophosphamide); and Vincristine
 * Murray, Sheila
 * [[Image:Tinysunfl.jpg]]Liles, Nikole

4. Cyle: Adriamycin (Doxorubicin); Etoposide(VP-16); Ifosfamide, and Vincristine (VIDE - 6 rounds)
 * Cycle: Vincristine, Ifosfamide, Etoposide (VIE - 7 rounds)
 * Cycle: Etoposide and Cytoxan (Cyclophosphamide) - (1 round)
 * [[Image:Tinysunfl.jpg]]Broude, Robert

5. Cyle: Adriamycin (Doxorubicin); Etoposide(VP-16); Ifosfamide, and Vincristine (VIDE - 6 rounds)
 * Middelman, Erik

6. Carboplatin; Dactiamycin; Epirubicin; Etoposid; Ifosfamide; and Vincristine
 * Kiyici, Michael

7. Adriamycin (Doxorubicin); Cisplatin; Etoposide(VP-16); Ifosfamide; and Vincristine
 * [[Image:Tinysunfl.jpg]]Abram, Jerry

8. Bleomycin; Etoposide(VP-16); Cisplatinum
 * [[Image:Tinysunfl.jpg]]Berman, Richard

9. Cisplatin; Decadron; Epirubicin; Etoposide(VP-16); Ifosfamide; D545 with Mesna Vincristine;
 * [[Image:Tinysunfl.jpg]]Zucca, David

10. Adriamycin (Doxorubicin); Cytoxan(Cyclophosphamide); Etoposide(VP-16); Ifosfamide;
 * [[Image:Tinysunfl.jpg]]Wilson, Michael

11. Adriamycin (Doxorubicin); Cisplatin, Paclitaxel, Ifosfamide with Mesna
 * [[Image:Tinysunfl.jpg]]Corry, Nicola

12. Cycle: Adriamycin (Doxorubicin); Cytoxan(Cyclophosphamide); Cisplatin
 * Cycle: ICE = Ifosmoside; Carboplatin; Etoposide
 * [[Image:Tinysunfl.jpg]]Denault, David

13. Cycle: Adriamycin (Doxorubicin); Cytoxan(Cyclophosphamide); Vincristine
 * Cycle: Cisplatin; Etoposide; Ifosfomide
 * [[Image:Tinysunfl.jpg]]Gibson, Sarah Taylor

14. Cycle: Adriamycin (Doxorubicin); Cisplatin; Vincristine
 * Cycle: ICE = Ifosmoside; Carboplatin; Etoposide
 * [[Image:Tinysunfl.jpg]]Hickie, Dustin

16. Actinomycin; Asparaginase; Hydroxyurea
 * [[Image:Tinysunfl.jpg]]Martinson, Chad

17. Cycle: Epirubicin, Ifosfamide with Mesna, Vincristine
 * Cycle: Cisplatinum; Etoposide
 * [[Image:Tinysunfl.jpg]]Mouktaroudes, Christos

18. Adriblastin (Doxorubicin) (4 days); Ifosfamide (3 days), Platinol (Cisplatin) (1 day) - 4 day cycles
 * [[Image:Tinysunfl.jpg]]Schlegel, Maria

19. Adriamycin (Doxorubicin); Ifosfamide (Ifex)
 * [[Image:Tinysunfl.jpg]]Scranton, Patrick

F. Other First Line Drugs

1. Vinblastin

2. Carboplatin
 * [[Image:Tinysunfl.jpg]]Martinson, Chad

Second Line Chemotherapy
A. Irinotecan and Temodar (Temozolimide)
 * Robertson, Nathan
 * Bodjanac, Nicole
 * Jenkins, Craig
 * [[Image:Tinysunfl.jpg]]Pusey, Jade

B. Adriamycin (Doxorubicin, Doxil) and Ifosfamide
 * Bender, Michael
 * [[Image:Tinysunfl.jpg]]Wilson, Derek

C. VIP-E - Etoposide (VP-16), Ifosfamide, Cisplatin, and Epirubicin
 * Falkenstein, Thomas

D. Irinotecan and oral Xeloda
 * [[Image:Tinysunfl.jpg]]Carfi, Christopher

E. Gleevec and Temodar
 * [[Image:Tinysunfl.jpg]]Carfi, Christopher

F. ICE = Ifosfamide, Carboplatin, Etoposide (VP-16)
 * [[Image:Tinysunfl.jpg]]Carfi, Christopher
 * [[Image:Tinysunfl.jpg]]Denault, David

G. Taxol and Carboplatin
 * [[Image:Tinysunfl.jpg]]Denault, David

H. Etoposide (VP-16); Cytoxan(Cyclophosphamide) (High dose for stem cell transplant)
 * [[Image:Tinysunfl.jpg]]Gibson, Sarah Taylor

I. Topotecan and Cytoxan(Cyclophosphamide)
 * [[Image:Tinysunfl.jpg]]Hickie, Dustin

J. Cycles: Cytoxan(Cyclophosphamide); Adriamycin (Doxorubicin, Doxil); Vincristine
 * Cycles: Etoposide (VP-16); Ifosfamide
 * [[Image:Tinysunfl.jpg]]Schafer, Ryan

K. Carboplatin; Cytoxan(Cyclophosphamide); Etoposide(VP-16) - 4 Cycles
 * [[Image:Tinysunfl.jpg]]Schafer, Ryan

Third Line and Other Chemo Combinations
A. CCT High-dose chemotherapy
 * Cyclophosphamide (Cytoxan) 1500 mg/m2
 * Carboplatin 200 mg/m2
 * Thiotepa 125 mg/m2
 * Falkenstein, Thomas

B.Cyclophosphamide (Cytoxan) and Topotecan

C.Docetaxel (Taxotere) and Gemcitabine (Gemzar)
 * Cloer, Rebecca

D.Cisplatnum and Etoposide (VP-16)
 * Cloer, Rebecca

E.Alimta and Cisplatnum
 * Ott, Keegan

F. Thalidomide, oral Etoposide (VP-16) , oral Cyclophosphamide (Cytoxin), Celebrex
 * [[Image:Tinysunfl.jpg]]Carfi, Christopher

G. Adriamycin (Doxorubicin), Cyclophosphamide (Cytoxin), Vincristine (higher dosage).
 * [[Image:Tinysunfl.jpg]]Carfi, Christopher

H. Thalidomide and Casodex (hormonal therapy drug)
 * [[Image:Tinysunfl.jpg]]Carfi, Christopher

I. Dactinomycin (Actinomycin), Ifosfamide, Vincristine
 * [[Image:Tinysunfl.jpg]]Carfi, Christopher

J. Bexarotene (Targretin) and ICE protocol : Ifosfamide, Carboplatin, Etoposide
 * [[Image:Tinysunfl.jpg]]Daunoras, Jay

K. Bexarotene (Targretin) and ICE protocol, Thalidomide
 * [[Image:Tinysunfl.jpg]]Daunoras, Jay

L. Adriamycin (Doxorubicin)(Doxil) and Thalidomide
 * [[Image:Tinysunfl.jpg]]Daunoras, Jay

M. Etoposide (Oral VP16), Thalidomide, Lupron
 * [[Image:Tinysunfl.jpg]]Daunoras, Jay

N. Carboplatin and Thiotepa (high dose chemotherapy for stem cell)
 * [[Image:Tinysunfl.jpg]]Daunoras, Jay
 * [[Image:Tinysunfl.jpg]]Lunchuck, Timothy

O. Cycle: Carboplatin and Paclitaxel (Taxol)
 * Cycle: Adriamycin
 * [[Image:Tinysunfl.jpg]]Denault, David

P. Methotrexate with Leucovorin
 * [[Image:Tinysunfl.jpg]]Martinson, Chad

Q. Irinotecan and Cisplatin
 * [[Image:Tinysunfl.jpg]]Martinson, Chad

R. Thiotepa; Cytoxan
 * [[Image:Tinysunfl.jpg]]Martinson, Chad

S. Cycle: Bleomycin; Methotrexate; Cisplatin; Vincristine
 * Cycle: Cytoxan (Cyclophosphamide); Actinomycin D; Vincristine
 * [[Image:Tinysunfl.jpg]]Schafer, Ryan

Single Chemotherapies
1. Actinomycin(Dactinomycin)

2. Adriamycin (Doxorubicin)(Doxil)
 * [[Image:Tinysunfl.jpg]]Daunoras, Jay

3. Alimta

4. Bexarotene (Targretin)
 * [[Image:Tinysunfl.jpg]]Daunoras, Jay

5. Casodex (Bicalutamide) - hormonal therapy used in prostrate cancer.

6. Celebrex (Celecoxib)

7. Cytoxan (Cyclophosphamide)
 * [[Image:Tinysunfl.jpg]]Denault, David

8. Decitabine
 * [[Image:Tinysunfl.jpg]]Wilson, Derek

9. Doxil - (doxorubicin HCl liposome injection}

10. Etoposide (Oral VP16)
 * [[Image:Tinysunfl.jpg]]Daunoras, Jay

11. Gleevec
 * Schaut, Nikki
 * [[Image:Tinysunfl.jpg]]Wilson, Derek
 * [[Image:Tinysunfl.jpg]]Liles, Nikole

12. Gemcitabine ( Gemzar )
 * [[Image:Tinysunfl.jpg]]Bishnow, Brian
 * [[Image:Tinysunfl.jpg]]Daunoras, Jay
 * [[Image:Tinysunfl.jpg]]Martinson, Chad
 * [[Image:Tinysunfl.jpg]]Scranton, Patrick

13. Irinotecan
 * [[Image:Tinysunfl.jpg]]Bishnow, Brian
 * [[Image:Tinysunfl.jpg]]Wilson, Derek

14. Lupron
 * [[Image:Tinysunfl.jpg]]Carfi, Christopher
 * [[Image:Tinysunfl.jpg]]Daunoras, Jay

15. Sirolimus (Rapamycin)
 * [[Image:Tinysunfl.jpg]]Daunoras, Jay

16. Thiotepa
 * [[Image:Tinysunfl.jpg]]Denault, David

17. Thalidomide
 * [[Image:Tinysunfl.jpg]]Wilson, Derek

18. Velcade (Bortezomib)
 * [[Image:Tinysunfl.jpg]]Martinson, Chad

Clinical Trials
See Groups by Clinical Trial

DSRCT References
Contact: dsrct.wiki@gmail.com

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